에이즈 치료, 획기적인 발전
에이즈 치료, 획기적인 발전
This is the CBS Evening News with Bob Schieffer. Two major scientific studies out today could lead to a breakthrough 큰 발전 in the treatment of AIDS and other diseases including cancer. Sharyn Alfonsi is here now with more on that. Sharyn?
Bob, well, one of the greatest mysteries of the AIDS epidemic 유행병 may be solved. 2 teams of scientists announced today that they know why the immune system 면역 시스템 is unable to control the HIV virus and more importantly, how we one…one day 언젠가는 might be able to manipulate 촉진하다 it to fight everything from HIV to cancer.
A healthy body generates something called T-cells or killer cells. It’s their job to attack viruses. But what scientists like Bruce Walker didn’t know until now is why those killer cells stopped working in most HIV patients. “One hypothesis 추측, 가정 has been that they become inactivated 활발치 않게 하다. One hypothesis is that…that they become destroyed and what this study shows is actually that the cells are there. They’re fully functional. It’s just that they have been turned off.”
Turned off by HIV. The virus disarms 무력하게 하다 T-cells by flicking off ~를 튀겨 날리다, 털어 버리다 a molecular switch 분자 스위치, <세포내 신호전달을 매개하는 단백질들> in the cells. In the laboratory, researchers were able to block that switch and restore T-cell function. The findings raised the possibility that one day doctors could switch a chronically ill 만성적 질환이 있는 patient’s immune system back on, so that it could resume its fight against HIV, cancer, or even hepatitis C C형 간염.
But there’s one big concern. By manipulating the immune system, you could send it into overdrive 과열상태, triggering 유발하다 autoimmune disease 자기면역질환 attacking healthy parts of the body. “We really don’t know what’s going to happen when we try and do this in humans. It opens a new pathway for us to pursue, but we really will need to proceed with caution.”
So this is an important development. But just to keep it in perspective 긴 안목에서, 진상을 바르게, it’s only been done in a test tube 시험관. Clinical trials 임상실험 with HIV positive patients will be the next telling 뚜렷한, 강력한 step. Bob? Alright, well, thank you, Sharyn.